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Joint estimation of effective population size and selection coefficient without neutrel markers: method validation and application to experimental evolution of viruses

Abstract : Experimental evolution studies deserve considerable attention to the estimation of basic evolutionary forces such as selection and genetic drift. With the advent of high-throughput sequencing techniques, these studies gained a renewed attention. However the joint estimation of selection and genetic drift still remain challenging when no neutral markers are available, a common situation with many microbes, such as viruses, due to their small tightly packed genomes.
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https://hal.inrae.fr/hal-02739698
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Submitted on : Tuesday, June 2, 2020 - 10:11:55 PM
Last modification on : Tuesday, October 19, 2021 - 7:00:46 PM
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  • HAL Id : hal-02739698, version 1
  • PRODINRA : 356641

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Elsa Rousseau, Benoît Moury, Ludovic Mailleret, Rachid Senoussi, Alain Palloix, et al.. Joint estimation of effective population size and selection coefficient without neutrel markers: method validation and application to experimental evolution of viruses. 13. International plant virus epidemiology symposium, Jun 2016, Avignon, France. 165 p. ⟨hal-02739698⟩

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