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Characterization of mucosa-associated Escherichia coli strains isolated from Crohn’s disease patients in Brazil

Abstract : Crohn’s disease (CD) is characterized by chronic inflammation of the human intestine. Several studies have demonstrated that the intestinal mucosa of CD patients in Western countries is abnormally colonized by adherent-invasive Escherichia coli (AIEC) strains. However, no studies to date have focused on the involvement of such E. coli strains in CD patients in Brazil. Here, we characterized E. coli strains associated with the ileal mucosa of Brazilian CD patients (ileal biopsies from 35 subjects, 24 CD patients and 11 controls).
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https://hal.inrae.fr/hal-02903480
Contributor : Sabine Julien <>
Submitted on : Tuesday, July 21, 2020 - 10:39:34 AM
Last modification on : Tuesday, September 7, 2021 - 3:44:02 PM

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Rafaella Costa, Maria Ferrari, Marie-Agnès Bringer, Arlette Darfeuille-Michaud, Flaviano Martins, et al.. Characterization of mucosa-associated Escherichia coli strains isolated from Crohn’s disease patients in Brazil. BMC Microbiology, BioMed Central, 2020, 20 (1), pp.178. ⟨10.1186/s12866-020-01856-x⟩. ⟨hal-02903480⟩

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