Skip to Main content Skip to Navigation
Journal articles

Spontaneous intake of essential oils after a negative postnatal experience has long-term effects on blood transcriptome in chickens

Abstract : Chicks subjected to early stressful factors could develop long-lasting effects on their performances, welfare and health. Free access to essential oils (EO) in poultry farming could mitigate these effects and potentially reduce use of antimicrobial drugs. This study on chicken analyzed long-lasting effects of post-hatch adverse conditions (Delayed group), and the impact of EO intake on blood physiological parameters and transcriptome. Half of the Control and Delayed groups had free access to EO, while the other half had only water for the first 13 days post-hatching. Blood analyses of metabolites, inflammation and oxidative stress biomarkers, and mRNA expression showed sex differences. Long-lasting effects of postnatal experience and EO intake persisted in blood transcriptome at D34. The early adverse conditions modified 68 genes in males and 83 genes in females. In Delayed males six transcription factors were over-represented (NFE2L2, MEF2A, FOXI1, Foxd3, Sox2 and TEAD1). In females only one factor was over-represented (PLAG1) and four under-represented (NFIL3, Foxd3, ESR2 and TAL1::TCF3). The genes showing modified expression are involved in oxidative stress, growth, bone metabolism and reproduction. Remarkably, spontaneous EO intake restored the expression levels of some genes affected by the postnatal adverse conditions suggesting a mitigating effect of EO intake.
Document type :
Journal articles
Complete list of metadata

https://hal.inrae.fr/hal-03179256
Contributor : Marion Desailly <>
Submitted on : Wednesday, March 24, 2021 - 11:09:10 AM
Last modification on : Monday, July 19, 2021 - 4:18:07 PM

File

2020-Foury-SR.pdf
Publisher files allowed on an open archive

Licence


Distributed under a Creative Commons Attribution 4.0 International License

Identifiers

Collections

Citation

Aline Foury, Anne Collin, Jean-Christophe Helbling, Christine Leterrier, Marie-Pierre Moisan, et al.. Spontaneous intake of essential oils after a negative postnatal experience has long-term effects on blood transcriptome in chickens. Scientific Reports, Nature Publishing Group, 2020, 10 (1), pp.1-14. ⟨10.1038/s41598-020-77732-5⟩. ⟨hal-03179256⟩

Share

Metrics

Record views

108

Files downloads

225