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Dépistage, prise en charge et suivi des personnes potentiellement surexposées à l’arsenic inorganique du fait de leur lieu de résidence

Abstract : Background and objectives. - The French national authority for health (Haute Autorite de sante: HAS) and the French clinical toxicology society (Societe de toxicologie clinique: STC) received a formal request from the French ministry for heath to elaborate recommendations for the screening of environmental overexposure to inorganic arsenic (iAs), for the medical management of overexposed patients and for the medical surveillance of exposed population. Methods. - The method used for the elaboration was the Clinical practice guidelines method recommended by HAS in this situation (HAS, 2010). Results. - The recommendations are presented in the present article. They concern: a) identification of those sites with a high risk of iAs overexposure for the residents (using bioaccessible concentrations in soils); the target population for Asi overexposure screening and screening modalities (using measurement of iAs and its metabolites in urine); b) the biomonitoring indications and modalities for overexposed individuals; c) the fraction of the population with iAs environmental exposure which should be the target for the detection and the diagnosis of complications, and the modalities of these operations; d) the treatment and prevention of iAs environmental overexposure. (C) 2020 Elsevier Masson SAS. All rights reserved.
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https://hal.inrae.fr/hal-03207828
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Submitted on : Monday, April 26, 2021 - 10:42:14 AM
Last modification on : Tuesday, June 15, 2021 - 2:57:32 PM

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R. Garnier, E. Nouyrigat, P. Benoit, J.-P. Goullé, C. Granon, et al.. Dépistage, prise en charge et suivi des personnes potentiellement surexposées à l’arsenic inorganique du fait de leur lieu de résidence. Archives des Maladies Professionnelles et de L'Environnement, Elsevier Masson, 2020, 81 (6), pp.770-796. ⟨10.1016/j.admp.2020.06.004⟩. ⟨hal-03207828⟩

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