Effect of the rheological properties of the liquid carrier on the in vitro swallowing of solid oral dosage forms - INRAE - Institut national de recherche pour l’agriculture, l’alimentation et l’environnement Accéder directement au contenu
Article Dans Une Revue Journal of Texture Studies Année : 2021

Effect of the rheological properties of the liquid carrier on the in vitro swallowing of solid oral dosage forms

Résumé

Solid oral dosage forms (SODF) are the most popular oral drug delivery forms, but they can be difficult to swallow, especially for patients suffering from swallowing disorders. This study investigated the dynamics of different combinations of liquid carriers and SODF during the oral phase of swallowing using an in vitro model. The rheological properties of the carriers were characterized using shear and extensional rheometry, and their effect on bolus velocity, bolus shape, post-swallow residues,
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Dates et versions

hal-03303381 , version 1 (29-07-2021)

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Anaïs Lavoisier, Sathyavageeswaran Shreeram, Michael Jedwab, Marco Ramaioli. Effect of the rheological properties of the liquid carrier on the in vitro swallowing of solid oral dosage forms. Journal of Texture Studies, 2021, ⟨10.1111/jtxs.12618⟩. ⟨hal-03303381⟩
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