The aim of our study was to describe the effect of stray voltages lower than 0.5 V on inflammation and oxidative status biomarkers in weaned piglets. The study was conducted on a nursery barn with two rooms of 12 pens of 38 28-day old piglets each, on two batches in France. In each pen, stray voltages were measured for each drinker and feeder every two weeks (9, 23, 37 and 50 days after inclusion). On the same days, two cotton ropes per pen were suspended for 30 min in order to collect oral fluid for salivary cortisol dosage. Two pigs per pen (84 pigs in total) were randomly selected at inclusion and blood sampled on days 9, 30 and 50 after weaning for the dosage of haptoglobin, hydroperoxides (HPO), and blood antioxidant potential (BAP). Pens were allocated to 4 groups based on their voltage levels in drinkers and feeders, with high (HVD, >125 mV) or low (LVD, <125 mV) voltage in drinkers and high (HVF, >50 mV) and low (LVF, <50 mV) voltage in feeders (LVD-LVF: n=24, LVD-HVF: n=15, HVD-LVF: n=26, HVD-HVF: n=19). Effects of voltage in drinkers, in feeders and their interaction on haptoglobin, HPO, BAP and salivary cortisol were analysed using a linear mixed model with pigs, pens and replicates as a random effect. Haptoglobin concentration was numerically higher in pigs exposed to HV in drinkers and feeders compared to the others, but without significance. HPO concentration tended to be affected by drinker × feeder voltage interaction (P=0.06). On day 50, HPO concentration was significantly higher in the group exposed to HV in both drinkers and in feeders compared to the 3 other groups (P=0.02). BAP and salivary cortisol concentrations were not different between groups. This is the first time that moderate consequences on oxidative status in weaned piglets of stray voltage lower than 0.5 V is reported in pigs. This suggested a possible detrimental effect for the health of pigs, but these results must be confirmed by further trials.