Is glycerol a good cryoprotectant for sperm cells? New exploration of its toxicity using avian model

In brief: Glycerol is a commonly used cryoprotectants for sperm cryopreservation in many species but shows cytotoxicity to decrease fertility. This study demonstrates that glycerol affects sperm migration and storage in the oviducts as well as negative modifications of sperm biology.

Keywords

cryoprotectant fertility glycerol sperm sperm storage tubules (SST) toxicity cryoprotectant fertility glycerol sperm sperm storage tubules (SST) toxicity cryoprotectant fertility glycerol sperm sperm storage tubules (SST) toxicity cryoprotectant toxicity

Domains

Reproductive Biology

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article1_glytoxic-spz_0510.pdf (1.96 Mo)

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https://hal.inrae.fr/hal-04230575

Submitted on : Tuesday, October 10, 2023-4:58:01 PM

Last modification on : Monday, July 1, 2024-3:34:05 PM

Dates and versions

hal-04230575 , version 1 (06-10-2023)

hal-04230575 , version 2 (10-10-2023)

Licence

Attribution - NonCommercial - NoDerivatives

Identifiers

HAL Id : hal-04230575 , version 2
DOI : 10.1016/j.anireprosci.2023.107330
PUBMED : 37734123
WOS : 001081614200001

Cite

Hsiu-Lien Herbie Lin, Pascal Mermillod, Isabelle Grasseau, Jean-Pierre Brillard, Nadine Gérard, et al.. Is glycerol a good cryoprotectant for sperm cells? New exploration of its toxicity using avian model. Animal Reproduction Science, 2023, 258, pp.107330. ⟨10.1016/j.anireprosci.2023.107330⟩. ⟨hal-04230575v2⟩

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